Conditions

Borderline personality disorder (BPD) is a severe mental health condition influenced by environmental risk factors (for example, interpersonal trauma) and genetic factors. We conducted the largest genome-wide association study (GWAS) meta-analysis of BPD so far, with a discovery sample of 12,339 cases and 1,041,717 controls, and a replication study of 685 cases and 107,750 controls…

Ultomiris has become one of the most important treatments in the rare disease space because of its ability to reduce the burden of chronic infusion therapy while improving patient outcomes across paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and generalized myasthenia gravis (gMG). As a long-acting C5 complement inhibitor, Ultomiris was developed as…