Daily weight-loss pill orforglipron approved in UK
Contact Us
Daily weight-loss pill orforglipron approved in UK
Anadolu Agency HEALTH
Published August 10,2026 04:06 PM
Updated August 10,2026 04:09 PM
Subscribe
A bottle of Eli Lilly’s Foundayo weight-loss pills in this undated illustration. (REUTERS File Photo)
A once-daily weight-loss pill that works in a similar way to injectable drugs such as Mounjaro has been approved for use in the UK
Orforglipron, which will be marketed under the name Foundayo, was authorized by the Medicines and Healthcare products Regulatory Agency (MHRA), making it “the first regulator in Europe” to approve the tablet for weight management and type 2 diabetes, according to the agency
The drug is manufactured by Eli Lilly and Company, which also makes Mounjaro, one of the best-known injectable medicines used for weight management and type 2 diabetes
“Following rigorous assessment of orforglipron’s safety, quality, and effectiveness, we are pleased to be the first regulator in Europe to authorize this tablet for weight management and type 2 diabetes,” Julian Beach, the MHRA’s executive director of healthcare quality and access, said in a statement on Monday
“As with all GLP-1 receptor agonists, this is a prescription-only medication, and the MHRA will keep the safety and effectiveness of orforglipron under close review.”
Orforglipron belongs to a class of medicines known as GLP-1 receptor agonists. It mimics the action of glucagon-like peptide-1, a hormone naturally released by the body after eating
The drug acts on areas of the brain involved in appetite regulation, helping people feel fuller for longer while reducing hunger and food cravings. It is intended to support <a href="https://healthylife7.com/eli-lillys-weight-loss-pill-wins-double-uk-approval/" title="Eli Lilly’s <a href="https://healthylife7.com/new-glp-1-pill-delivers-up-to-12-weight-loss-in-36-weeks/" title="New GLP-1 pill delivers up to 12% weight loss in 36 weeks”>weight loss pill wins double UK approval”>weight loss alongside an appropriate diet and lifestyle
For people with type 2 diabetes, orforglipron can also help reduce high blood sugar levels
Unlike injectable weight-loss medicines, the treatment is taken once a day as a tablet. It can be taken at any time of day, with no restrictions on food or water intake
Treatment starts at 0.8 mg and increases through doses of 2.5 mg, 5.5 mg, 9 mg, 14.5 mg and 17.2 mg. Patients should spend at least one month at each dose level and follow the instructions provided in the patient information leaflet
The most common side effects of orforglipron include nausea, constipation, diarrhoea, vomiting, indigestion and abdominal pain
The approval comes as demand for weight-loss medicines continues to grow in the UK
Despite the UK regulatory approval, Foundayo is not currently available through the National Health Service (NHS)
As with other newly approved treatments, any decision on whether the drug should be made available through the NHS will follow established processes, including an assessment by the National Institute for Health and Care Excellence (NICE), the MHRA said
