Cadence has raised $100 million to expand an AI-powered chronic care platform that now treats more than 100,000 patients and, according to the company, saves Medicare roughly $2.7 million each week. Spark Capital led the Series C, with participation from Thrive Capital, General Catalyst, Coatue, B Capital, Corewell <a href="https://healthylife7.com/wildfire-smoke-prompts-health-warnings/” title=”Wildfire Smoke Prompts Health Warnings”>Health Ventures, Memorial Hermann, and Duke Health. Cadence plans to use the funding to add health system partners, develop its AI agents, and expand its work in value-based care
The company now works with more than 20 health systems and announced new affiliations with Duke Health and Texas Health Rel records and clinical workflows, Cadence’s supervised AI agents monitor patient vitals, support medication adjustments, and provide personalized lifestyle coaching between office visits. The company tripled its annual recurring revenue in 2025
Cadence says its platform has reduced hospital admissions by 27% and lowered annual healthcare costs by $1,302 per patient across peer-reviewed studies and real-world deployments. Its AI agents currently resolve 55% of incoming vitals alerts without human adjustment, while maintaining a median response time of 3.5 minutes
“We built Cadence to solve the clinical labor constraint at the heart of the chronic disease crisis,” said Founder and CEO Chris Altchek. He said the new funding will help build the infrastructure needed to expand from 100,000 patients to millions
Spark Capital Partner and new Cadence Board Member Will Reed said the company had already demonstrated clinical outcomes, earned the trust of major health systems, and shown that AI could be deployed safely inside care delivery. Cadence’s broader goal is to automate routine chronic care work so clinicians can focus on decisions that require direct medical judgment


