Lead
A New Scientific Review Challenges One of the Most Popular Diet Trends
A comprehensive analysis of more than 350 studies suggests eating less protein—not more—may promote healthier aging and a longer life, especially among sedentary adults
Aug 2, 2026
Photo: Getty
Listen to this ArticleMore info
0:00 / 0:00
A growing body of research suggests that eating less protein, not more, may help people live longer and stay healthier as they age, particularly if they are not physically active
A review published Friday in the scientific journal Cell Press Blue analyzed findings from more than 350 previously published studies examining the relationship between protein consumption, metabolism, and aging
“Despite widespread recommendations for higher protein intake during aging, increasing evidence suggests that dietary protein restriction (PR) promotes metabolic health, healthspan, and lifespan across diverse organisms,” University of Wisconsin-Madison researchers and wrote
The comprehensive analysis comes as high-protein foods and drinks marketed for <a href="https://healthylife7.com/amy-schumer-shows-off-her-glp-1-weight-loss-progress-in-bikini-no-filter-as-per-ushe/" title="Amy Schumer Shows Off Her GLP-1 Weight Loss Progress in Bikini: ‘No Filter As Per Ushe’”>weight loss, fitness, and healthy aging continue to surge in popularity. “Because most people are relatively sedentary,” Lamming, the review’s corresponding author, said in a statement, “many people are likely consuming more protein than they actually need, which probably has negative health consequences.”
Featured Video
An Inc.com Featured Presentation
According to the paper, lower protein intake appears to improve metabolism across a wide range of species, from yeast and fruit flies to rodents and humans. It alters nutrient-sensing pathways, reduces cellular damage, and preserves healthy cell function. Several studies cited in the review found that reducing protein intake improved blood sugar control and led to weight loss, even when more calories were consumed
The researchers point to a hormone called fibroblast growth factor 21, or FGF21, as one of the primary drivers behind those beneficial effects. FGF21 levels rise when protein intake falls and have been linked to greater energy expenditure, improved glucose control, and lower inflammation
The review also highlighted several amino acids—including methionine, isoleucine, and valine—that may play an outsized role in aging-related processes. Restricting those amino acids in animal studies has been associated with improvements in metabolic health, fewer signs of frailty, and a longer lifespan
