HEALTH WELLNESS
Weight Loss
A new weight loss study found something surprising about muscle loss
New clinical research found that participants taking Calocurb lost weight, reduced body fat and maintained lean muscle mass over 24 weeks
Trisha EastoUSA TODAY
July 26, 2026, 2:27 p.m. ET
- Calocurb is a dietary supplement made from a bitter hops extract called Amarasate.
- A recent clinical study found participants taking Calocurb lost an average of 8.3 pounds over 24 weeks while preserving lean muscle mass.
- The supplement is designed to naturally support GLP-1 activation to help reduce hunger and cravings.
- Unlike some GLP-1 medications, Calocurb is reported to have no ongoing side effects, though some users may experience initial mild digestive discomfort.
Muscle loss has become one of the biggest concerns surrounding popular GLP-1 weight loss treatments. While these medications can help people lose significant amounts of weight, some studies suggest a portion of that weight may come from lean muscle mass
Now, a new clinical study published by Obesity Pillars is drawing attention for a different reason. Researchers found that participants taking Calocurb, a dietary supplement formulated with a New Zealand hops extract called Amarasate, lost an average of 8.3 pounds over 24 weeks while maintaining lean muscle mass
The findings are generating interest among consumers looking for alternatives to prescription weight-loss medications or ways to support their weight-management goals
Here’s what the study found and what to know about Calocurb before trying it
How much does Calocurb cost?
For a limited time only, you can save 10% on your first Calocurb purchase when you use our exclusive promo code USATODAY10 at checkout—making this the perfect time to begin your health journey. Please note that this promo code is only valid for the one-time purchase option and cannot be combined with any other offers or discounts
Calocurb GLP-1 Activator
This natural appetite control supplement is made from New Zealand hops. Save 10% with code USATODAY10
How does Calocurb work?
Calocurb naturally supports GLP-1 activation to help reduce your cravings and hunger, helping you stay on track of your nutrition, weight and overall health goals. The key ingredient is Amarasate, which is an extract from New Zealand hops flowers
Does Calocurb cause side effects?
No. Calocurb has no ongoing side effects, with only 5% of users experiencing mild digestive discomfort in the first 24–72 hours as the body adjusts to naturally increased GLP-1 levels. Calocurb recommends gradually increasing your dose over several days can help ease any initial discomfort
Get started with Calocurb today
How often should I take Calocurb?
Calocurb recommends starting with one capsule per day, one hour before a meal. Then, they recommend increasing your dose to two capsules twice daily, one hour before meals, over five days. Here’s what the schedule looks like to build up your dose to the maximum recommended amount:
- Day 1 – 2:Â Take one capsule one hour before a meal.
- Day 3 – 4:Â Take one capsule twice daily, one hour before meals.
- Day 5+:Â Take two capsules twice daily, one hour before meals.
- Max:Â Four capsules daily.
Calocurb says the best results occur when the supplement is taken on an empty stomach, one hour before meals. The effects of Calocurb can last for up to six hours after taking a capsule. You can tailor your dosage daily, taking up to four capsules
How much can you save on Calocurb?
A one-time, one-month supply of Calocurb, which includes 90 pills or 45 servings, costs $89.99. Plus, you can save an extra 10% when you use our exclusive promo code USATODAY10 at checkout
Alternatively, you can subscribe to regular deliveries and save nearly 15%, bringing your cost down to just $76.54. You can choose the frequency that works for you—every one, two or three months. Please note that subscription discounts cannot be combined with additional promo codes
Can Calocurb help with weight loss?
A new randomized, double-blind, placebo-controlled clinical study found that participants who took Calocurb for 24 weeks lost an average of 8.3 pounds (3.77 kg), compared with 0.88 pounds (0.4 kg) among those who received a placebo. Researchers also reported greater reductions in body fat and visceral fat among the Calocurb group without a significant loss of lean muscle mass
However, that doesn’t mean everyone who takes Calocurb will lose 8.3 pounds. Results can vary, and the study participants also received healthy diet and exercise guidance throughout the trial
Calocurb is a dietary supplement, not a prescription weight loss medication, and you should always consult your healthcare provider if you have concerns or medical conditions
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