Browsing: Conditions

There are extensive ongoing efforts to slow or even reverse human aging, such as with epigenetic cellular reprogramming, thymus rejuvenation or senolytics. In parallel, new and diverse metrics—known as biological clocks—have been discovered and shown to track the pace of aging in an individual and their organs, tissues and cells. These clocks have multiple potential…

Rare and undiagnosed diseases pose diagnostic challenges due to phenotypic and genetic heterogeneity and the limitations of conventional molecular testing. As part of the RareBoost project, we implemented an integrated, stepwise genomic strategy in a cohort of 134 patients from 120 families with previously inconclusive genetic testing. Our strategy combined systematic exome sequencing with subsequent…

The psychiatric safety profile of glucagon-like peptide-1 receptor agonists (GLP-1RAs) is characterized by inconsistent findings during active treatment and remains largely unexplored after cessation. Here we show that GLP-1RA discontinuation is associated with an increased risk of psychiatric events. Using large-scale electronic health records from the Shanghai Hospital Link Database, we investigate incident depressive and…

INCREASED awareness and therapeutic advancements may be associated with a reduction in diagnosis delays of primary hyperoxalurias (PH) in France, which has clinical implications for overall prognosis according to a new retrospective study

The Pros and Cons of a Full-Body MRI Search AdvertisementAdvertisement July 9, 2026/Health Conditions/Cancer Care & Prevention