Browsing: Weight Loss

The regulatory mechanism of leptin’s afferent action in the brain is contingent upon the efferent sympathetic innervation of white and brown adipose tissues. Nonetheless, the peripheral regulation governing the afferent–efferent balance remains ambiguous. Here we show the enriched expression of both leptin receptor (Lepr) and β2-adrenergic receptor (Adrb2) in perineurial cells that form a barrier…

Nearly half of all American adults have high blood pressure. That represents roughly 120 million people, and most will eventually be encouraged to take medication. But blood pressure roulette is an uncomfortable way to describe what often happens next: a doctor chooses a drug, writes a prescription and waits to see what happens. Will it…