Browsing: Cells

Type 2 inflammation is coordinated by remarkably durable CD4+ T helper 2 (TH2) cell responses, yet the cellular architecture that drives this chronic inflammation and prevents exhaustion remains poorly understood. To define the TH2 landscape in chronic type 2 inflammation, we established a mouse model of long-term pulmonary allergen exposure, finding that type 2 inflammation…

Every time your body fights a virus, cells are making split-second decisions that determine whether an infection spreads or stops. Some sacrifice themselves to protect the tissue around them. Others are hijacked before they get the chance. A Virginia Tech virologist just won a rare federal award to find out what tips the balance

A rare population of immune cells may play a central role in sustaining the body’s response to chronic diseases, including persistent infections, autoimmune disorders, and potentially cancer

A University of Miami Miller School of Medicine study found that damaged mitochondrial DNA can continue accumulating in dopamine-producing neurons long after the initial injury occurs, offering new insight into why these cells are especially vulnerable in Parkinson’s disease

“A collaborative team from Weill Cornell Medicine andMemorial Sloan Kettering Cancer Center has uncovered a fundamental mechanism that helps the immune system sustain its supply of disease-fighting T cells during chronic illness