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1 weight-loss drugs such as Mounjaro and Wegovy can affect a woman’s chances of becoming pregnant, prompting a series of warnings that call for caution. On social media, users are sharing accounts of unexpected pregnancies while taking the drugs, coining terms like “Mounjaro baby” and “Wegovy baby.”
Pregnancy should be avoided while taking GLP-1 drugs, according to Britain’s Medicines and Healthcare products Regulatory Agency (MHRA). The medications should not be used by women who are pregnant, trying to conceive or breastfeeding, and anyone who discovers they are pregnant during treatment should consult a doctor
The MHRA specified that women planning a pregnancy should stop taking Wegovy (whose active ingredient is semaglutide) at least two months before trying to conceive, and Mounjaro (whose active ingredient is tirzepatide) at least one month before. The precautionary measure is needed because there is not enough safety data on the use of GLP-1 drugs during pregnancy
Women who take Mounjaro and oral contraceptives at the same time need particular caution. Tirzepatide slows the rate at which the stomach empties, a process that may affect the absorption and effectiveness of oral contraceptives. The MHRA therefore advises patients to add a barrier method such as condoms, or to use a non-oral contraceptive, for four weeks after starting Mounjaro treatment and for four weeks while the dose is being increased
According to the British daily The Guardian, the MHRA received more than 40 pregnancy-related reports involving users of GLP-1 drugs last year. Of these, 26 reports involved tirzepatide, the active ingredient in Mounjaro, the highest number for any single drug. Not all of the reported cases represent unintended pregnancies
Mounjaro Prescriptions Top 1.5 Million in 10 Months
Meanwhile, as South Korea’s weight-loss drug market grows rapidly, prescriptions of the GLP-1 drug Mounjaro have surpassed 1.5 million just 10 months after its launch. According to Drug Utilization Review (DUR) data submitted to Rep. Han Ji-a of the People Power Party, a member of the National Assembly’s Health and Welfare Committee, by the Health Insurance Review and Assessment Service, Mounjaro — launched in South Korea last August — was prescribed a total of 1,501,161 times over the 10 months through this May.
Because Mounjaro and Wegovy are not covered by insurance, official prescription volumes are difficult to compile. As a result, records checked by medical institutions through the DUR system serve as a key indicator for gauging actual prescribing trends
#Mounjaro#Wegovy#GLP1#WeightLossDrugs#MHRA#Pregnancy#Fertility
Original reporting by Kim Su-ho for Seoul Economic Daily
AI-translated from Korean. Quotes from foreignxact original wording
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