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Still in the dark: effects of sex differences on statin-associated diabetes risk

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Statins reduce cardiovascular risk but modestly increase type 2 diabetes (T2D). Evidence is limited by underrepresentation of women and lack of sex-specific analyses. In an umbrella review and meta-analysis of 21 trials with sex-disaggregated data, statins increased T2D risk similarly in women (OR 1.28) and men (OR 1.24). However, absence of study-level data precluded assessment…