Browsing: fatty

The liver just might be one of your hardest-working organs, producing proteins and filtering the blood, metabolizing nutrients and creating necessary bile for digestion. But sometimes the liver can develop abnormalities that can inhibit its function, such as fatty liver. You might think of alcohol as a potential cause, but this isn’t the only cause.…

People with MASLD have an elevated risk of cardiovascular disease, cognitive decline, and other metabolic complications, yet the biological mechanisms connecting these conditions remain incompletely understood. In a new study published in the journal Aging, researchers investigated whether lipocalin-2 (LCN2), a protein involved in inflammatory and metabolic signaling, is associated with early vascular dysfunction, cognitive…

An experimental drug developed at Michigan Medicine has shown the ability to reverse severe fatty liver disease in animal studies by restoring gut health. The findings, published in The Journal of Clinical Investigation, suggest that targeting the connection between the gut and liver could offer a promising new approach for treating metabolic dysfunction-associated steatohepatitis (MASH)